2-Fluoro-6-methoxyphenylboronic acid CAS 78495-63-3 is an aromatic boronic acid used primarily as a building block in palladium-catalyzed cross-coupling, especially Suzuki–Miyaura reactions. I recommend buyers evaluate it by verified identity, assay, water content, physical form, packaging, and batch documentation rather than by price alone. The molecular formula is generally represented as C7H8BFO3, with a calculated molecular weight of approximately 169.95 g/mol. At Maison Chemical, we help research, process development, and procurement teams confirm the right specification before quotation and shipment.
If you are looking for more details, kindly visit our website.
This guide is intended for medicinal chemistry teams, pharmaceutical and agrochemical research groups, custom synthesis companies, universities, and distributors purchasing this intermediate for laboratory or process-development work. It is also useful for buyers comparing several suppliers for the same CAS number. The purchasing decision should reflect the intended reaction, required quantity, documentation level, and timeline.
I do not recommend treating a CAS number as a complete quality specification. CAS 78495-63-3 helps identify the target substance, but it does not by itself define assay, residual solvents, particle size, packaging, or shelf-life expectations. These details should be confirmed through a current technical data sheet, certificate of analysis, and commercial quotation.
2-Fluoro-6-methoxyphenylboronic acid contains an aryl boronic acid group together with fluoro and methoxy substituents on the aromatic ring. The boronic acid functionality is the main reactive handle used in many carbon–carbon bond-forming applications. The fluoro and methoxy groups remain part of the final aryl fragment and can influence the electronic and steric behavior of the substrate during synthesis.
In practical purchasing terms, this is a specialty organic boronic acid rather than a general-purpose commodity solvent or reagent. Its performance depends on chemical identity and handling history, including exposure to moisture, heat, and unsuitable storage conditions. I advise buyers to request storage recommendations and retest requirements when material will be held for an extended period.
Before placing an order, I suggest building a specification sheet around the actual reaction and downstream use. The following reference information can support an initial inquiry, but the supplier’s batch-specific documentation should control the final acceptance decision.
| Item | Purchasing relevance |
|---|---|
| Product name | 2-Fluoro-6-methoxyphenylboronic acid |
| CAS number | 78495-63-3 |
| Approximate molecular formula | C7H8BFO3 |
| Approximate molecular weight | 169.95 g/mol |
| Typical use category | Aryl boronic acid building block for synthetic research |
| Documentation to request | COA, SDS, specification sheet, packing details, and lot information |
For reaction development, buyers commonly focus on assay, water content, and impurity profile because these factors can affect reagent equivalence and reaction reproducibility. However, I avoid assigning a universal purity value without a batch-specific report. If your process requires a defined assay, such as a minimum percentage, state that requirement in the inquiry and ask whether the result is measured by HPLC, NMR, titration, or another documented method.
The most direct application is the preparation of biaryl or heteroaryl products through Suzuki–Miyaura coupling with a suitable aryl or heteroaryl halide. The boronic acid group provides the transferable aryl unit, while the fluoro and methoxy substituents can contribute to the structure and properties of the target molecule. For discovery chemistry, small packs may be appropriate when several analogues are being screened.
Process teams should evaluate more than nominal assay. They may need consistent lot-to-lot quality, controlled packaging, sufficient reserve stock, and clear impurity information to support route optimization. A material that is adequate for early screening may require additional documentation or tighter controls before it is selected for a larger campaign.
Custom synthesis organizations and distributors may prioritize continuity of supply, packing formats, export documentation, and predictable communication. I recommend confirming whether the quoted material is available from existing stock, planned production, or a new manufacturing schedule. This distinction can affect lead time and purchasing risk.
For more information, please visit Maison Chemical.
Start by specifying the intended use, estimated order quantity, target assay, acceptable impurity profile, and required delivery date. A laboratory order may be measured in grams, while process development may require hundreds of grams or more; the commercial conditions can differ substantially. Also identify whether the product will be used for internal research, customer supply, or a regulated development program.
Ask for the product name, CAS number, molecular formula, molecular weight, appearance, storage conditions, and analytical method used for release testing. Compare the information across the quotation, SDS, specification sheet, and COA. If any document shows inconsistent naming or formula information, resolve the discrepancy before purchase.
Boronic acids should be handled according to the supplier’s documented storage instructions. I recommend checking whether the package is suitable for the quantity, whether the container protects the material from moisture, and whether the label includes lot number and retest or expiry information when applicable. A clear packaging plan is especially important when the material will be transported internationally.
Request the minimum order quantity, available pack sizes, production lead time, sample policy, payment terms, and shipping options in writing. Lead time can vary depending on inventory, batch scheduling, quality review, and destination requirements, so I do not advise relying on a generic promise such as “immediate delivery.” Buyers should also ask whether a pre-shipment document review is available.
The price of 2-Fluoro-6-methoxyphenylboronic acid can change with order size, assay requirement, packaging, testing scope, production status, and shipping destination. A lower unit price may not represent a lower total cost if it requires a large MOQ, creates excess inventory, or provides insufficient documentation. I recommend comparing the complete delivered offer rather than comparing only the price per gram.
For small research purchases, availability and sample support may be more important than volume pricing. For larger requirements, buyers should assess whether the supplier can reserve a production slot and maintain consistent specifications across lots. A practical quotation should state the currency, Incoterm where applicable, packing configuration, estimated lead time, and validity period.
At Maison Chemical, I support buyers by organizing product information around identity, specification, quantity, documentation, packaging, and delivery requirements. We can discuss whether your request is for laboratory research, process development, distribution, or a larger procurement program. This allows the quotation to reflect the actual use case instead of providing an unsuitable standard offer.
When you contact us, please include the required quantity, target specification, destination country, desired delivery date, and documentation expectations. If you already have an internal specification, sharing it helps us evaluate alignment more efficiently. We can then provide the applicable commercial information and clarify available supply options without making unsupported claims about a batch that has not yet been selected.
The best way to purchase 2-Fluoro-6-methoxyphenylboronic acid CAS 78495-63-3 is to match the material specification to the intended synthesis and then evaluate the supplier’s documentation, packaging, availability, and commercial terms. I recommend requesting a current COA and SDS, confirming the required quantity and delivery date, and checking the analytical method before approving the order. These steps reduce avoidable uncertainty without assuming that every supplier or batch has identical performance.
If you are sourcing this compound for research, process development, or distribution, send Maison Chemical your target quantity, specification, destination, and timeline. We will review the request and help you identify the appropriate product and supply arrangement for your purchasing needs.
If you are looking for more details, kindly visit 2-Fluoro-6-methoxyphenylboronic acid CAS 78495-63-3.